Phytochemical analysis and biological activities of ethanolic extract of Curcuma longa rhizome

Abstract Curcuma longa is an important dietary plant which possess several pharmacological activities, including antioxidant, antimicrobial, anti-inflamatory, anticancer and anti clotting etc. The aim of the present study was to determine phenolic profile in vitro antioxidant antidiabetic activities. In HPLC chromatogram rhizome extract 15 compounds were identified namely Digalloyl-hexoside, Caffeic acid hexoside, Curdione, Coumaric, acid, Sinapic Qurecetin-3-D-galactoside, Casuarinin, Bisdemethoxycurcumin, Curcuminol, Demethoxycurcumin, Isorhamnetin, Valoneic bilactone, Curcumin, Curcumin-O-glucuronide respectively. ethanolic displayed IC50 value 37.1±0.3 µg/ml against alpha glucosidase. DPPH radical scavenging activity 27.2 ± 1.1 ?g/mL. It concluded that long rich source curcumin contain phenolics. glucosidase inhibitory effect justifies its popular use traditional medicine.